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Porous nanoparticles

SupraVail® Porous Nano Matrix

High Drug Loading for Poorly Soluble Pharmaceutical Actives!


SupraVail® Porous Nano Matrix from Phares boosts the dissolution rate of lipophilic, hydrophobic and amphipathic compounds by leveraging the enormous specific surface area of a highly porous, nano-scale carrier.

  • Formulation strategy is suitable for oral administration
  • Specific surface area of sponge-like carrier > 100 m2/g
  • Drug coats the pores of the particles like a film
  • Particles are highly dispersed throughout the GI tract
  • Establishes optimal conditions for drug absorption
  • Especially suited for high drug loading
  • Can be filled into gelatine capsules or be tableted
  • Manufacture with standard solids-handling equipment

Secret behind SupraVail® Porous Nano Matrix

SupraVail® Porous Nano Matrix formulation strategy takes advantage of the tremendous specific surface area (100-300 m2/g) of the carrier to accelerate the dissolution rate of the pharmaceutical active. At the same time, the carrier itself is less than 500 nm in dimension, permitting it to be very finely dispersed in the gastrointestinal tract. The photo series above demonstrates the evolution of the formulation from an easy-to-handle powder, suitable for capsule filling or tableting, to a highly disperse system. SupraVail® Porous Nano Matrix provides optimal conditions for drug absorption in the gastrointestinal tract.

For more information, click here to download the SupraVail® Porous Nano Matrix Brochure.

 
 

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