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S.C / I.M depots

The subcutaneous and intramuscular routes of administration are another option for parenteral drug delivery. In the case of poorly soluble compounds, the SupraVail® Membrane Lipid Matrix formulations represent a particularly attractive strategy for delivering drugs.

The phospholipids used in the SupraVail® Membrane Lipid Matrix are well-tolerated in s.c. and i.m. applications, and similar to their use in oral, intravenous and topical applications, they have the ability to solubilize hydrophobic and lipophilic compounds. By preventing precipitation of the active, they also promote local tolerability by avoiding the irritation caused by precipitated drug crystals.

Finally, depending on the membrane transfer properties of the molecule and the exact composition of the formulation, the release rate of drug from the depot can be rapid or take place over a longer period.

 
 

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